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The story continues where the first season left off only months into the future. Yuokai Gakuen has been repaired and the new semester is underway. Tsukune and gang are back, and more powerful then ever. Anti-Thesis's true identity is relieved. With new adversaries looming on the horizon, and something much more sinister then the gang has ever faced before. Tsukune is battling with the monster inside him. With the help of Moka, Mizore, Kurumu, Ruby, and Yukari. Tsukune trains to get his vampire blood under control and the strength to protect what he holds dear. The new season focuses more on the girls, their past, and their families. New confrontations await them. New friends and allies will join them by their side. Together they will discover the secrets of Moka's rosary, and her lineage...
By a bizzare coincidence, Tsukune Aono has accidentally gotten himself admitted to a youkai acadamy, a school attended by monsters (youkai). Just when he thinks he'll run away from there, he meets the beautiful girl Moka and his mood turns ultra happy. However, she transforms into her true form when the rosary on her chest is taken off, she's a super vampire!